The Vampire Universe is the alternate reality where most of the people have become vampires. Once Spider-Man and Kid Arachnid arrived, they helped Blood Spider (the Spider-Man of the universe) in defeating the enemy and cleansing the people of their curse, turning them and Lizard King human again.
After Lizard King took power, he forced all the vampire factions under his rule and became so powerful. After taking half the planet, the Lizard King took Blood Spider's team and turned them into vampires under his control.
At some point, Wolf Spider became the latter's second-in-command and they put New York in chaos.
- Blood Spider/Peter Parker
- White Tiger/Ava Ayala
- Iron Fist/Danny Rand
- Power Man/Luke Cage
- Lizard King/Curt Connors