Season 4: Ultimate Spider-Man vs The Sinister 6
Ultimate Spider-Man vs The Sinister 6 Logo
Background Information
Name: Season 4: Ultimate Spider-Man vs The Sinister 6
Created by: Stan Lee
Steve Ditko
Written by: Kevin Burke
Chris "Doc" Wyatt
Young Ki Yoon
Paul Giacoppo
Mairghread Scott
Geoffrey Thorne
Matt Wayne
Gavin Hignight
Jacob Semahn
Joshua Fine
Andrew Robinson
Henry Gilroy
Joshua Hale Fialkov
Marty Isenberg
Elliott Casey
Country of origin:

United States

No. of Episodes:


About the Show
Statue: On-Air
Networks: Disney XD - USA

Disney Channel - USA
YTV - Canada



As the fourth and final season begins, Doctor Octopus allies himself with Arnim Zola and HYDRA and begins to form a new iteration of the Sinister Six starting with Kraven the Hunter. When Doctor Octopus attempts to turn Norman Osborn back into Green Goblin, he finds that Osborn injected himself with an anti-Goblin serum to prevent further transformations. Doctor Octopus uses the Siege Perilous to summon the Green Goblin's demonic winged counterpart from Miles Morales's universe and after a brief battle recruits him instead. Then it is revealed that Rhino has become a spy for Doctor Octopus while operating as a student at the S.H.I.E.L.D. Academy in exchange for finding a cure for his condition (since he gained his powers by drinking one of Doctor Octopus's animal serums). When Spider-Man and his team accidentally release the water-made criminal Hydro-Man, Doctor Octopus spares no expense in recruiting him. Doctor Octopus then completes his lineup with Electro. Spider-Man fights evil with the help of S.H.I.E.L.D. and his own new team consisting of Agent Venom, Iron Spider, Miles Morales (going by the name Kid Arachnid ever since ending up on Spider-Man's world), and the newly-introduced Scarlet Spider (who has no identity and is later named Ben by Aunt May). It was later revealed that Scarlet Spider was the real spy for Doctor Octopus, while Rhino only busted Doctor Octopus out of his cell for the cure and unmasks Spider-Man in front of Doctor Octopus, revealing his identity. Doctor Octopus reveals that he gave Scarlet Spider his powers with one purpose in mind, to gain Spider-Man's trust, then stab him in the back to show that his faith in others can be a weakness. This leads to Doctor Octopus leading up to his next plot that has him turning against Arnim Zola. Though Scarlet Spider has a change of heart at the last minute, he ends up sacrificing himself to save the city from Doctor Octopus.

Soon after, Spider-Man discovers the reason behind Fury and Nova's disappearance; they were protecting Madame Web from HYDRA, but were ultimately discovered and Fury was held hostage by HYDRA and Crossbones. After Fury was rescued by Spider-Man, Web and Triton, Fury and Web went into hiding again to protect themselves from HYDRA, with Fury leaving Spider-Man in complete control of S.H.I.E.L.D. during his absence. Then Crossbones and Michael Morbius do some experiments with the Venom symbiote which leads to the revival of Carnage leading up to Carnage's explosion causing every civilian to turn into Carnage-like monsters. Spider-Man then joins forces with Captain America to battle against the Carnages. Harry awakens from his coma and reverts back into Anti-Venom, and begins to drain the Carnage symbiotes away from the civillians. After losing control, Peter reveals his identity to Harry, who reverts back to himself, before re-emerging with Anti-Venom to destroy the Carnage symbiotes. Afterwards, Harry learns that Flash Thompson is Agent Venom. The Carnage symbiote revealed itself to still be alive, however, and goes on a rampage throughout the city in direction of Midtown High to find Mary Jane Watson, who was overtaken by the Carnage symbiote to become the "Carnage Queen". They are attacked by Morbius, who became a living vampire due to the injection he received from Doctor Octopus. Spider-Man, Agent Venom and Harry Osborn ultimately save Mary Jane from the symbiote after revealing their identities to her, and she destroyed the symbiote herself. Unbeknownst to Spider-Man, a fragment of the Carnage symbiote is inside her body.

Later on, when Spider-Ham and Spyder-Knight appear in New York, Madame Web comes to the conclusion that the destruction of the Siege Perilous during the fight with Doctor Octopus and alternate Green Goblin has shattered the dimensional barriers between numerous worlds. Spider-Man and Miles Morales travel to alternate realities in order to collect the pieces of the Siege Perilous, but an evil version of Spider-Man named Wolf Spider seeks to reassemble the pieces in his plans to conquer the multiverse by draining the life force of all other spider-powered individuals, and becoming the most powerful of them all. During their adventure, they reunite with Spider-Man Noir and meet other spider-based characters like Blood Spider, Web Beard the Pirate, and Webslinger the Spider Cowboy as they work to get to the Siege Perilous shards before Wolf Spider does. They find the last piece in Miles' native dimension, where they learn that since he and the demonic Goblin left, crime got even higher, and the universe's native Aunt May, feeling that it needs a Spider, used leftover equipment from the universe's native Peter Parker (who died in a fight with the demonic Green Goblin) to turn one of his friends Gwen Stacy into a new spider-powered hero, Spider-Woman. Together with her, they repair the Siege Perilous, but Wolf Spider manages to swipe it and go forth with his plan. Luckily, Spider-Man manages to deceive his evil counterpart into absorbing too much power, causing him to explode, which sends the life force of the other spiders back to their native homes. Although they have the Siege Perilous, Miles, after seeing how well Spider-Woman has done with protecting his universe, decides to let her remain as the main spider-powered person of it, while he and his mother, Rio Morales, permanently settle in Spider-Man's native dimension.

In a similarity to the Clone Saga, Spider-Man and Mary Jane soon discover the clone of Spider-Man called Kaine who tries to feed off them. The clone of Spider-Man eventually leads them to "Project Kaine" which involves combining the DNA of Spider-Man with the Synthezoids. Surprisingly, Mary Jane able to control the Carnage Symbiote inside her, thanks to Dr. Connors experiment and assumes the identity of Spider-Woman. It is discovered that Doctor Octopus and Arnim Zola had created Scarlet Spider as part of Weapon S which are Spider-Man/Synthezoid Spider-Slayers where he is to have been the leader of the Delta-Nine Synthezoids. When Scarlet Spider gets control of the Delta-Nine Synthezoids and Doctor Octopus reclaims his Nanotech that gives him a more mobile body, Spider-Man's group causes HYDRA Island to sink into the water again. Back to Triskelion, the other team of Spider-Man: Nova, Power Man, Iron Fist and Squirrel Girl attacks Scarlet Spider and the Delta-Nine Synthezoids, because they know Scarlet Spider worked for Doctor Octopus, not only knows Spider-Man's identity, but also endangered S.H.I.E.L.D. Academy and Aunt May, being all against him. Kaine returns and draining the energies of it's inhabitants enough to leave them with coma-like symptoms, he targets the spider-based characters. Web Warrriors fight Kaine, but he´s gets control of the Delta-Nine Synthezoids, Spider-Man and the other spider-based characters must defeat Kaine even when he combines with the Delta-Nine Synthezoids to form a hybrid form called The Ultimate Spider-Slayer, until Agent Venom saved Scarlet and uses the energy transmitter to overload to explode.

Then the graduation day comes in which Doc Ock warns Peter Parker that he should never become Spider-Man and save his Aunt May from dying. Spider-Man quickly goes to the Triskelion and assembles all the Web-Warriors and New Warriors, and tells them about what happened in the morning. In the series' climax, Doctor Octopus along with his Superior Sinister Six captures Spider-Man and uses an antidote on him due to which he loses his spider powers but after working with Norman Osborn at Oscorp who now knows that Peter Parker is Spider-Man, Spider-Man is able to gain back his spider powers and uses the antidote to cure Vulture, Rhino, and a Lizard-mutated Crossbones and defeating Scorpion and Kraven. With the same antidote, Spider-Man also defeats Doctor Octopus in his mindless Octopus monster form, on which Octavius is eventually convinced that Spider-Man shows respect on him despite all difficulties and redeems himself by helping Spider-Man undo the force-field he projected to destroy Spider-Man's teammates and graduation attendants. In the epilogue, Doctor Octopus eventually surrenders as he is taken under custody by Iron Man, Spider-Man successfully graduates as Agent Venom and Scarlet Spider are named the new teachers in S.H.I.E.L.D. Academy. After a conversation with his Aunt May (after moving to another home), Peter eventually takes on his old super hero life satisfied to have finally become what he trained in S.H.I.E.L.D. to be: The Ultimate Spider-Man.


Main Characters

Supporting Characters


Other Characters



Main Cast

Actor/Actress Character/s
Drake Bell Spider-Man/Peter Parker
Cameraman (Miles From Home)
Automated Voice (Double Agent Venom)
Spider-Punk/Peter Parker
Zombie Princess (Strange Little Halloween)
Little JJJ (Strange Little Halloween)
Dee Bradley Baker Lizard/Dr. Curt Connors
S.H.I.E.L.D. Agent#2 (Lizards)
Sandman/Flint Marko
Sandy (Beached)
HYDRA Soldier (Anti-Venom)
Carnage (The Symbiote Saga: Part 1)
Lizard King/Curt Connors
Ogie Banks Kid Arachnid/Ultimate Spider-Man/Miles Morales
Power Man/Luke Cage
Vampire Power Man/Luke Cage
Eric Bauza Iron Spider/Amadeus Cho
Computer Voice (Lizards)
S.H.I.E.L.D. Agent (Force of Nature)
Greg Cipes Iron Fist/Danny Rand
Tom Kenny Doctor Octopus/Dr. Otto Octavius
S.H.I.E.L.D. Agent (Hydra Attacks: Part 1)
Vulture/Adrian Toomes
Doc Ock Holiday/Otto Octavius
HYDRA Security Transmission Voice (The Spider Slayers: Part 2)
Matt Lanter Agent Venom/Flash Thompson
Patrioteer/Harry Osborn
Misty Lee Aunt May Reilly Parker
Woman (Hydra Attacks: Part 1 and The New Sinister Six: Part 2)
Squirrel Girl/Doreen Green
Oscorp Computer Voice (Graduation Day: Part 2)
Caitlyn Taylor Love White Tiger/Ava Ayala
Chi McBride Nick Fury
Logan Miller Nova/Sam Alexander
Scott Porter Scarlet Spider/Ben Reilly
Synth-Scarlet Spiders
Tara Strong Spider-Woman/Carnage Queen/Mary Jane Watson
S.H.I.E.L.D. Computer Voice (The Symbiote Saga: Part 3)
Mary Jane Watson Noir
Steven Weber Iron Patriot/Norman Osborn
Ultimate Green Goblin/Norman Osborn
Trapster/Peter Petruski

Additional Cast

Actor/Actress Character/s
Diedrich Bader Kraven the Hunter/Sergei Kravinoff
HYDRA Soldier (Double Agent Venom)
Moon Knight/Marc Spector
Troy Baker Web-Slinger/Peter Parker
Christopher Daniel Barnes Spyder-Knight/Peter Parker
Wolf Spider/Peter Parker
Video Game Voice (Return to the Spider-Verse: Part 1)
Clancy Brown Phantom Rider/Ben Parker
Thunderbolt/Thaddeus Ross
Iain De Caestecker Leo Fitz
Dove Cameron Spider-Gwen/Gwen Stacy
Police officer (Return to the Spider-Verse: Part 4)
María Canals-Barrera Rio Morales
Robert Clotworthy George Stacy
Trevor Devall Rocket Raccoon
Benjamin Diskin Morbius the Living Vampire/Dr. Michael Morbius
Blood Spider/Peter Parker
Spider-Ham/Peter Porker
Ashley Eckstein Dagger/Tandy Bowen
Shriek/Frances Barrison
Will Friedle Web Beard/Peter Parker
Grant George Ant-Man/Scott Lang
Ninja (Strange Little Halloween)
Werewolf (Strange Little Halloween)
Seth Green Howard the Duck
A-Bombardier/Rick Jones
Mark Hamill Arnim Zola
Elizabeth Henstridge Jemma Simmons
Danny Jacobs Baron Karl Mordo
Vampire (Strange Little Halloween)
Man (Strange Little Halloween)
Phil LaMarr Cloak/Tyrone Johnson
S.H.I.E.L.D. Agent#1 (Lizards)
Stan Lee Stan
Rose McGowan Medusa/Medusalith Amaquelin
Liam O'Brien Doctor Strange/Stephan Strange
Adrian Pasdar Iron Man/Tony Stark
Rob Paulsen Batroc the Leaper/Georges Batroc
Computer Voice (Iron Vulture)
Jon Polito Hammerhead/Joseph Lorenzini
Kevin Michael Richardson Groot
Daryl Sabara Rhino/Alexander Sytsevich
Paul Scheer Mysterio/Quentin Beck
Roger Craig Smith Captain America/Steve Rogers
Ghost Spider
Cree Summer Madame Web/Julia Carpenter
Vampire White Tiger/Ava Ayala
Fred Tatasciore Crossbones/Brock Rumlow
HYDRA Soldier (Agent Web)
Hulk/Dr. Bruce Banner
Shield-Head Carnage (The Symbiote Saga: Part 2)
Giant Carnage (The Symbiote Saga: Part 3)
Mr. Fixit/Joe Fixit
Dragon Goon#1 (Return to the Spider-Verse: Part 3)
James Arnold Taylor Triton
Hydro-Man/Morris Bench
Robot (Force of Nature)
Computer Voice (Agent Web)
Milo Ventimiglia Spider-Man Noir/Peter Parker
Mary Kate Wiles Mysterio/Frances Beck
Imari Williams Bone Spider
Goliath Spider
Keone Young Mr. Negative/Martin Li
Dragon Goon#2 (Return to the Spider-Verse: Part 3)


  • This season takes place between Seasons 2 and 3 of Avengers Assemble, due to the fact that Captain America still wears his uniform from Seasons 1-2, Ant-Man still being with the Avengers and Crossbones still wears his costume and mask from Season 1. By Ultron Revolution, Captain America has a new uniform, Ant-Man has relocated to California and Crossbones has a new costume and mask. Additionally, it was stated in Ultron Revolution that Hydra is a fraction of its original strength, which was due to Spider-Man defeating them during this season.
  • This season had Doctor Octopus as the main antagonist, HYDRA as the secondary antagonists and the Sinister Six as the tertiary antagonists.
  • The Sinister Six that are seen in the poster had Doctor Octopus, Rhino, Kraven the Hunter, Electro, Lizard and Green Goblin.
    • However the difference is that Lizard was only seen once and never joined the group again, Green Goblin never returned and got replaced by his Ultimate counterpart and Electro was only in one iteration of the group.


Community content is available under CC-BY-SA unless otherwise noted.